Detection of Transplanted Cells

Detection of transplanted cells in transplantation studies

Allogeneic transplantation

For allogeneic transplants, XY chromosome FISH probes are used for detection of transplanted cells. Usually we detect Y-positive male donor cells.

Detection of transplanted male cells in mouse live

Y:yellow, X:red

Detection of transplanted male cells in mouse heart

Y:yellow, X:red

Detection of fused cells in male-cell-transplanted mouse liver

Y:yellow, X:purple

Detection of transplanted male cells in pig cartilage

Detection of transplanted male cells in a paraffin section of rat lung

Heterologous transplantation

Using our species specific FISH probes, we can detect transplanted cells in Heterologous transplants. FISH signals are big and bright, so that transplanted cells can be seen even in low magnification.

Detection of transplanted human cells in a paraffin section of mouse kidney

Human:yellow, Mouse:red

Detection of transplanted human cells in a paraffin section of rat lung

Human:yellow, Rat:red

FISH detection by Species Specific FISH probes on mixture of metaphase spreads from 2 species

1. Human(yellow) / Mouse(red)
2. Human(yellow) / Rat(red)
3. Human(green) / Pig(red)
4. Human(green) / Pig(red)