Analysis of Chromosomal Abnormalities

• Multi color FISH analysis for human and mouse chromosomes (analysis of abnormalities in chromosome number and chromosome structure)
• Karyotype analysis with conventional Giemsa staining (human, mouse, rat, hamster, chicken, etc.)

Multi color FISH analysis

Karyotiping of human chromosomes by multicolor FISH probes

Karyotiping of mouse chromosomes by multicolor FISH probes

Trisomy 11 and translocation of chromosome 16 were observed in this mouse cell line.

Karyotiping of rat chromosomes by multicolor FISH probes

In the case of rat chromosomes, chromosome 13 and chromosome 14 are stained in same color. So we recognize them by the shape of chromosomes.

Karyotype by conventional chromosome bandings (G-band, Q-band)

Q-banding analysis of human cells Trysomy 21 47,XX,+21

G-banding analysis of human cells normal 46,XY

Karyotype analysis with conventional Giemsa staining

Normal mouse chromosomes

Tetraploid

Translocation