Transgene Mapping

• Chromosome mapping of cDNA or genomic DNA fragment on banded chromosomes  (human, mouse, rat, hamster, chicken, snake, etc.)
• Comparative chromosome mapping between different species
• Detection of chromosomal deletion / amplification in tumor cell lines

Comparative chromosome mapping among human, rat and mouse probed with human cDNA using direct R-banding FISH method

Transgene mapping on mouse chromosomes using direct R-banding FISH method

Transgene mapping with M-FISH

For transgene mapping or gene mapping analysis on cells with chromosomal abnormalities, we can use the FISH mapping technique with M-FISH to determine chromosomes.

Gene mapping on chicken chromosomes using direct R-banding FISH method

Transgene mapping on CHO cells using direct R-banding FISH method

Homozygote / heterozygote analysis in transgenic mouse